CH6008 - DRUGS AND PHARMACEUTICAL TECHNOLOGY (Syllabus) 2013-regulation Anna University

CH6008 - DRUGS AND PHARMACEUTICAL TECHNOLOGY (Syllabus) 2013-regulation Anna University

CH6008

DRUGS AND PHARMACEUTICAL TECHNOLOGY

 LPTC

3003

OBJECTIVES:
To give the students an understanding of the polytechnical nature of engineering and drug discovery in the pharmaceutical industry involving Chemical Engineering.

UNIT I

INTRODUCTION

9

Development of drugs and pharmaceutical industry; organic therapeutic agents uses and economics

UNIT II

DRUG METABOLISM AND PHARMACO KINETICS & MICROBIOLOGICAL AND ANIMAL PRODUCTS

9

Drug metabolism; physico chemical principles; pharma kinetics-action of drugs on human bodies. Antibiotics- gram positive, gram negative and broad spectrum antibiotics; hormones


UNIT III

IMPORTANT UNIT PROCESSES AND THEIR APPLICATION

9

Chemical conversion processes; alkylation; carboxylation; condensation and cyclisation; dehydration, esterification, halogenation, oxidation, sulfonation; complex chemical conversions fermentation.

UNIT IV

MANUFACTURING PRINCIPLES & PACKING AND QUALITY CONTROL

9

Compressed tablets; wet granulation; dry granulation or slugging; advancement in granulation; direct compression, tablet presses formulation; coating pills; capsules sustained action dosage forms; parential solutions, oral liquids; injections; ointments; standard of hygiene and manufacturing practice. Packing; packing techniques; quality control.

UNIT V

PHARMACEUTICAL PRODUCTS & PHARMACEUTICAL ANALYSIS

9

Vitamins; cold remedies; laxatives; analgesics; nonsteroidal contraceptives; external antiseptics; antacids and others. Analytical methods and tests for various drugs and pharmaceuticals – spectroscopy, chromatography, fluorimetry, polarimetry, refractometry, pHmetry

TOTAL : 45 PERIODS

OUTCOMES:
Students will be equipped with the knowledge to transform raw materials into useful pharmaceutical and fine chemical products with commercial interest through systematic use of engineering concepts and methods

TEXT BOOK:
1. Rawlines, E.A.; “ Bentleys Text book of Pharmaceutics “, III Edition, Bailliere Tindall, London, 1977.

REFERENCES
1. Yalkonsky, S.H.; Swarbick. J.; “ Drug and Pharamaceutical Sciences “, Vol. I, II, III, IV, V, VI and VII, Marcel Dekkar Inc., New York, 1975.
2. “Remingtons Pharmaceutical Sciences “, Mack Publishing Co., 1975.

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