PL6008 - BIOMEDICALS PLASTICS (Syllabus) 2013-regulation Anna University

PL6008 - BIOMEDICALS PLASTICS (Syllabus) 2013-regulation Anna University

PL6008	BIOMEDICALS PLASTICS	LPTC

3003

OBJECTIVES: To enable the students

• To understand various natural and synthetic polymers used for biomedical applications and their compatibility with biological system.
• To learn about the plastics that are used as implants in cardiovascular, ophthalmology, and other artificial organs.
• To be familiarized with the polymers used in dental applications.

UNIT I		9

BIOMATERIALS: Biomaterials, BioCompatibility, Stabilization, Inflammation And Wound Healing, Blood Clotting System, kinn System, Biological response to Implants, Implant Design And Applications.

UNIT II		9

BIOMEDICL POLYMERS: Criteria for the Selection of Biomedical Polymers Physicochemical Aspects of the Blood Compatibility of Polymeric Surface. Biomedical Polymers from biological source, Poly hydroxy Alkanoic Acids, Microbial polysaccharides, Silk, Collagen. , Microbial Cellulose, Hyaluronic Acid, Synthetic Polymers such as PMMA, Silicon Rubber, Polyethylene, Natural Rubber, Hydrogels.

UNIT III		9

BIOMEDICAL APPLICATIONS OF POLYMERS: Permanent Implants For Function- Orthopedics, Cardio Vascular, Respiratory Patches And Tubes, Digestive System, Genitourinary System, Nervous System, Orbital (Corneal And Lens Prosthesis) –Permanent Implant For Cosmoses, Other Applications Of Engineered Material In Clinical Practices, Silicone Implants. Polymer Membranes, Polymer Skin, Polymeric Blood.

UNIT IV		9

POLYMERIC LENSES: Contact Lenses, Hard Lenses, Gas Permeable Lenses, Flexible Lenses, Soft Lenses, Hydrogels, Equilibrium Swelling, Absorption And Desorption, Oxygen Permeability, Types of Soft Lenses, Manufacture, Cleaning And Disinfection.

UNIT V		9

DENTAL POLYMERS: Dental applications, denture bases, dentate reliners, crown and bridge resins, plastic teeth, mouth protectors, maxillofacial prosthetic materials, restorative material, polyelectrolyte based restoratives, sealants, adhesives, dental impression and duplicating materials, agar, algmater elastomers.

TOTAL : 45 PERIODS

OUTCOMES:

Students would understand about various plastics that are used for biomedical applications such as cardiovascular, dental, ophthalmology, and other artificial organs. Students also understand the compatibility of biomedical polymers with biological systems.

TEXT BOOKS:

1. Bio-materials, An Introduction – J B Park, Pleneum Press.
2. Plastics Materials – J S Brydson.
3. H.F. Mark (Ed), Encyclopedia of polymer science and engineering, John Wiley and Sons New York, 1989.

REFERENCES

1. Comprehensive Polymer Science Vol.7 Alcock., Contemporary Polymer Chemistry.
2. Second Ed. Manas Chanda, Salil K. Roy (Ed) Plastic Technology Hand Book Marcel Dekker, Inc. New York, 1993
3. B.Sedlacek, C.G.Overberger, J.F.Mark, (ed.) Medical polymers: Chemical problems.
4. Boretos; John W., Concise Guide to Biomedical Polymers, Charles C. Thomas Publishers, Springfield (1973).
5. Chiellini; Emo, Sunamoto; Junzo, Migliaesi; Claudio, Ottebrite; Raphael and Cohn; Daniel (Eds.), Biomedical Polymers and Polymer Therapeutics, Kluwer Academic/Plenum Publishers, New York (2001).
6. Galaev; Igor and Mattiasson; Bo (Eds.), Smart Polymers; Applications in Biotechnology and Biomedicine, CRC Press, Boca Raton (2008).
7. Gebelin; Charles G. and Carraher Jr.; Charles E. (Eds.), Polymeric Materials in Medication, Plenum Press, New York (1985).[CN90]