BT8302 - APPLIED THERMODYNAMICS FOR BIOTECHNOLOGISTS (Syllabus) 2017-regulation Anna University

BT8302 - APPLIED THERMODYNAMICS FOR BIOTECHNOLOGISTS (Syllabus) 2017-regulation Anna University

BT8302

APPLIED THERMODYNAMICS FOR BIOTECHNOLOGISTS

 LPTC

3003

OBJECTIVE:
• To enable the students to learn about basic concepts of classical and statistical thermodynamics

UNIT I

THERMODYNAMIC LAW AND PROPERTIES OF FLUIDS

9

First Law of thermodynamics, a generalized balance equation and conserved quantities, Volumetric properties of fluids exhibiting non ideal behavior; residual properties; estimation of thermodynamic properties using equations of state; calculations involving actual property exchanges; Maxwell’s relations and applications.

UNIT II

SOLUTION THERMODYNAMICS

9

Partial molar properties; concepts of chemical potential and fugacity; ideal and non-ideal solutions; concepts and applications of excess properties of mixtures; activity coefficient; composition models; Gibbs Duhem equation.


UNIT III

PHASE EQUILIBRIA

9

Criteria for phase equilibria; VLE calculations for binary and multi component systems; liquid-liquid equilibria and solid-solid equilibria.

UNIT IV

CHEMICAL REACTION EQUILIBRIA

9

Equilibrium criteria for homogeneous chemical reactions; evaluation of equilibrium constant; effect of temperature and pressure on equilibrium constant; calculation of equilibrium conversion and yields for single and multiple reactions.

UNIT V

THERMODYNAMIC DESCRIPTION OF MICROBIAL GROWTH AND PRODUCT FORMATION

9

Thermodynamics of microbial growth stoichiometry thermodynamics of maintenance, Calculation of the Operational Stoichiometry of a growth process at Different growth rates, Including Heat using the Herbert –Pirt Relation for Electron Donor, thermodynamics and stoichiometry of Product Formation

TOTAL : 45 PERIODS

OUTCOMES: At the end of the course,the student will have the ability
• To explain the theoretical concepts of thermodynamics and how it applies to energy conversion in technological applications and biological systems.
• To demonstrate the capability to analyze the energy conversion performance in avariety of modern applications in biological systems.
• To design and carry out bioprocess engineering experiments, and analyze and interpret fundamental data to do the design and operation of bioprocesses.
• To describe the criteria when two phases coexist in equilibrium and the vapour liquid equilibrium calculations microbial growth and product formation.

TEXT BOOKS:
1. Smith J.M., Van Ness H.C., and Abbot M.M. “Introduction to Chemical Engineering Thermodynamics”, VIth Edition. Tata McGraw-Hill, 2003.
2. Narayanan K.V. “A Text Book of Chemical Engineering Thermodynamics”, PHI, 2003.
3. Christiana D. Smolke, “ The Metabolic Pathway Engineering Handbook Fundamentals”, CRC Press Taylor & Francis Group, 2010.

REFERENCE:
1. Sandler S.I. “Chemical and Engineering Thermodynamics”, John Wiley,1989.

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