PY6006 - CHEMISTRY OF NATURAL PRODUCTS (Syllabus) 2013-regulation Anna University

PY6006 - CHEMISTRY OF NATURAL PRODUCTS (Syllabus) 2013-regulation Anna University

PY6006

CHEMISTRY OF NATURAL PRODUCTS

 LPTC

3003

OBJECTIVE:
To provide the knowledge about the natural products, isolation and characterization of their active substances from their botanical source.

UNIT I

STRUCTURAL BASIS OF NATURAL PRODUCTS

9

Chemical and spectral approaches to simple molecules of natural origin. Identification of natural products by chromatographic and spectroscopic methods and application of I.R., N.M.R. and Mass spectroscopy in the structural elucidation of organic compounds.

UNIT II

GLYCOSIDES

8

Classification, biosynthetic studies and basic metabolic pathways, introduction to biogenesis of secondary metabolites, chemistry, general methods of extraction, isolation, chemical tests, medicinal properties of cardinolides and bufadienolides, digoxin and digitoxin.


UNIT III

ALKALOIDS

12

Classification, chemistry, general methods of extraction, isolation, chemical tests, and structural elucidation of Pyridine alkaloids, Tropane alkaloids, Quinoline and Isoquinoline alkaloids, Phenanthrine alkaloids, Indole alkaloids, Imidazole alkaloids, Alkaloid amines, Glycoalkaloid, Xanthine alkaloid

UNIT IV

TERPENES AND FLAVONOIDS

8

Classification, biosynthetic studies and basic metabolic pathways, introduction to biogenesis of secondary metabolites, chemistry, general methods of extraction, isolation, chemical tests, medicinal properties and structural elucidation, flavonoids, quercetin; Terpenes– special isoprene rule, and structural elucidation of citral, carvone, menthol and camphor.

UNIT V

STUDY OF TRADITIONAL DRUGS

8

Classification of indigenous drugs traditional drugs, common vernacular names, botanical source, chemical constituents, uses and marketed formulations with ingredients like – Amla, Satavari, Bhilwua, guggul, gymnema, neem ,tulsi, Shilajit and Spirulina

TOTAL : 45 PERIODS

OUTCOMES: The student will be able
• To classify extract, isolate and characterize the natural products by chemical tests.
• To understand the classification, metabolic pathways, metabolites and their structural elucidation.

TEXT BOOKS:
1. O.P. Agarwal,Chemistry of Natural Products (Vol.-1 & 2),41st edition,Goel publishing house, 2013
2. Gurdeep Chatwal, Organic Chemistry of Natural Products (Vol.-1 & 2) . Himalaya Publishing House. 1986
3. I.L.Finar, “Organic chemistry” Volume 2, 5th edition, Pearson education pvt.Ltd.

REFERENCES:
1. Varro E. Tyler, Lynn R. Brady, James E. Robbers, Pharmacognosy Lea & Febiger, 1981.
2. Trease, G. E. and Evans, W.C. Pharmacognosy, Published by Elsevier, a Division of Wallis, T.E. Textbook of Pharmacognosy, 15th Edition, CBS Publishers .

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