PY6401 - UNIT OPERATIONS IN PHARMACEUTICAL INDUSTRY (Syllabus) 2013-regulation Anna University

PY6401 - UNIT OPERATIONS IN PHARMACEUTICAL INDUSTRY (Syllabus) 2013-regulation Anna University

PY6401

UNIT OPERATIONS IN PHARMACEUTICAL INDUSTRY

 LPTC

3003

OBJECTIVE:
To provide the basic fundamentals and various unit operations such as filtration, centrifugation, crystallization, refrigeration, air-conditioning and evaporation.

UNIT I

MATERIALS OF PHARMACEUTICAL PLANT CONSTRUCTION

9

Overview of composition, corrosion, resistance, properties and applications of the materials of construction with special reference to stainless steel and glass, Industrial Hazards and Safety Precautions – Mechanical, Chemical, Electrical, Fire and Dust hazards, Industrial dermatitis, Accident records, etc.

UNIT II

FILTRATION AND CENTRIFUGATION

9

Theory of filtration, filter aids, filter media, industrial filters including filter press, rotary press, rotary filter, edge filter, etc. Factors affecting filtration, mathematical problems on filtration, optimum-cleaning cycle in batch filters. Principles of centrifugation, industrial centrifugal filters and centrifugal sedimenters,


UNIT III

CRYSTALLIZATION

9

Characters of crystals like purity, size, shape, geometry, habit, forms, size and factors affecting them. Solubility curves and calculation of yields. Material and heat balances around Swenson Walker crystalliser, Super saturation theory, its limitations, nucleation mechanism and crystal growth. Study of various types of crystallisers. Caking of crystals and its prevention and numerical problems on yields.

UNIT IV

HUMIDITY CONTROL, REFRIGERATION AND AIR- CONDITIONING

9

Basic concepts, definition, wet bulb and adiabatic saturation temperatures, psychometric chart and measurement of humidity, application of humidity measurement in pharmacy. Equipments for dehumidification operations, principle and applications of refrigeration and air conditioning.

UNIT V

EVAPORATION

9

Basic concepts of phase equilibrium, factors affecting evaporation, evaporators, film evaporators, single effect and multiple effect evaporators and Mathematical problems on evaporation.

TOTAL (L:45 + T:15) : 60 PERIODS

OUTCOMES: The student will be able to
• Understand the various categories of materials used in pharmaceutical industry. • Understand the fundamental concepts of filtration, centrifugation, crystallization, refrigeration and air-conditioning, apply their applications in pharmaceutical industry.

TEXT BOOKS:
1. McCabe WL, Smith J.C and Harriott “Unit operations of Chemical Engineering” McGraw Hill International Book Co. London 2004.
2. Girish K.Jani, “Pharmaceutical Engineering I, Unit Operation I” B.S.Shah Prakashan, India, 2006.

REFERENCES:
1. Badger, W.L and Banchero, J.T “Introduction to Chemical Engineering” Tata McGraw Hill, 2002
2. Ballaney, “Refrigeration and Air conditioning” Tata McGraw Hill, 2000
3. Coulson, J.M. and Richardson, J.F.”Chemical Engineering” 3rd Edition, Butterworth Heineman Publication, 2001.

Comments

Popular posts from this blog

CS3491 Syllabus - Artificial Intelligence And Machine Learning - 2021 Regulation Anna University

CS3401 Syllabus - Algorithms - 2021 Regulation Anna University

CS3492 Syllabus - Database Management Systems - 2021 Regulation Anna University