PY6701 - ADVANCED DRUG DELIVERY SYSTEM (Syllabus) 2013-regulation Anna University

PY6701 - ADVANCED DRUG DELIVERY SYSTEM (Syllabus) 2013-regulation Anna University

PY6701

ADVANCED DRUG DELIVERY SYSTEM

 LPTC

3003

OBJECTIVES: To enable the students to
• Understand the properties of polymer and its significance in drug delivery systems.
• Interpret physicochemical properties of the drug with the drug delivery system modules.
• Apply the concepts of newer method of drug delivery systems involved in the pharmaceutical sciences and relevance of their drug delivery strategies.

UNIT I

POLYMERS

9

Polymers used in controlled drug delivery modules – Classification – Advantages and disadvantages of polymers – Polymer Characterisation - Various classes of controlled release systems.

UNIT II

SUSTAINED RELEASE FORMULATIONS

9

Introduction, concept, advantages and disadvantages. Physicochemical and biological properties of drugs relevant to sustained release formulations.


UNIT III

TRANSDERMAL DRUG DELIVERY SYSTEMS

9

Permeation through skin – factors affecting permeation – basic components of TDDS – permeation enhancers – formulation approaches used in development of TDDS and their evaluation.

UNIT IV

TARGETED DRUG DELIVERY SYSTEMS

9

Concepts – Advantages and disadvantages – Nanoparticles – Liposomes – Microspheres – Magnetic microspheres.

UNIT V

DRUG DELIVERY LARGE MOLECULES

9

Delivery system for Peptides and Proteins – Delivery of nucleic acids – Antibodies and siRNA.

TOTAL (L:45 + T:15) : 60 PERIODS

OUTCOMES: The student will be able to
• Understand the properties and importance of polymer in novel drug delivery systems.
• Understand the application of polymer in sustained release, topical and targeted drug delivery systems.

TEXT BOOKS:
1. Vyas S.P., Khar R.K, “Targeted & Controlled Drug Delivery: Novel Carrier Systems”, CBSPD, 2006.
2. Junginger H.E “Drug Targeting and Delivery- concepts in dosage form design” EllisHarwood series in Pharmaceutical Technology

REFERENCES:
1. Vasant Ranade , mannfred A Hollinger “Drug delivery systems” II ed , CRC Press.
2. Grietje Molema and Dirk K F Meijer “Drug Targetting organ-specific strategies” WILEY- VCH , 2001
3. Anya M Hillery et al “ Drug Delivery and Targeting”, CRC Press, 2010.

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