PY8001 - BASIC LABORATORY ANIMAL SCIENCE (Syllabus) 2017-regulation Anna University

PY8001 - BASIC LABORATORY ANIMAL SCIENCE (Syllabus) 2017-regulation Anna University

PY8001

BASIC LABORATORY ANIMAL SCIENCE

 LPTC

3003

OBJECTIVES:
• The objective of this course is to present basic facts and principles that are essential for the humane use and care of laboratory animals and for the quality of research.
• The objective of these courses is to present basic and appropriate biology, care, health and management of animals, recognition of pain, suffering and distress in these animals and minimally invasive procedures without anaesthesia to be applied on these animals.
• This course meets the standards for the species-specific education and training requirements for persons designing projects and procedures for these specific animals.

UNIT I

FUNDAMENTALS OF LABORATORY ANIMAL SCIENCE

9

Contribution of Laboratory animals to Medical Progress: Past, Present and Future. Overview of ethics of animal research.

UNIT II

LABORATORY ANIMAL CARE

9

Animal accommodation, animal care routines, animal health and hygiene, diets, feeding and drinking, reproduction, breeding and heredity.


UNIT III

GLOBAL REGULATIONS

9

An overview of global and Indian legislation, regulation and policies about experimentation on laboratory animals.

UNIT IV

PRE-CLINICAL RESEARCH

9

Animal models, concepts, classification of animal models and disease models, extrapolation from animals to humans, model body size and scaling.

UNIT V

ALTERNATIVES TO ANIMAL TESTING

9

Alternatives to animal models,refinement, reduction, and replacement of animal uses in the life sciences.

TOTAL : 45 PERIODS

OUTCOMES: The student would able to
• Describe the requirements of various legislation concerning scientific use of animals.
• Identify ethical issues in human-animal interaction, including replacement, reduction and refinement.
• Describe normal behaviour of rodents and lagomorphs, handling, husbandry needs, and enrichment and also could be able to describe the need for hygiene in animal housing and experimental work.

TEXT BOOKS:
1. Introduction to Laboratory Animal Science and Technology J. K. INGLIS. Pergamon Press, Elsevier; 2013.
2. Hau, Jann, and Steven J. Schapiro, eds. Handbook of laboratory animal science: essential principles and practices. Vol. 1. CRC press, 2002
3. Fundamentals of Laboratory Animal Science, Anqi Li, Jianglin Fan, CRC press,2017.

REFERENCES:
1. Handbook of Laboratory Animal Science 2nd Edition, Edited by Jann Hau and Gerald L.Van Hoosier Jr. Vol, I, II, III. 2004.
2. Management of laboratory animal care and use programs. Edited by Mark A. Suckow, Fred A Douglas, Robert H Weichbrod, 2001.
3. Conn, P.M., Animal models for the study of human disease. Academic Press, 2017.

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