PY8018 - PHARMACEUTICAL NANOTECHNOLOGY (Syllabus) 2017-regulation Anna University

PY8018 - PHARMACEUTICAL NANOTECHNOLOGY (Syllabus) 2017-regulation Anna University

PY8018

PHARMACEUTICAL NANOTECHNOLOGY

 LPTC
3003

OBJECTIVE:
• The goal of this course is to provide an insight into the fundamentals of nanotechnology in biomedical and Pharmaceutical research. It will also guide the students to understand how nanomaterials can be used for a diversity of analytical and medicinal rationales

UNIT I

NANOSTRUCTURES

9
Preparation, properties and characterization - Self-assembling nanostructure - vesicular and micellar polymerization-nanofilms - Metal Nanoparticles- lipid nanoparticles- nanoemulsion - Molecular nanomaterials: dendrimers, etc.,

UNIT II

NANOTECHNOLOGY IN BIOMEDICAL INDUSTRY

9
Reconstructive Intervention and Surgery- Nanomaterials in bone substitutes and dentistry – Implants and Prosthesis -in vivo imaging- genetic defects and other disease states –– Nanorobotics in Surgery –Nanocarriers: sustained, controlled, targeted drug delivery systems


UNIT III

NANOTECHNOLOGY IN CANCER THERAPY

9
Cancer Cell Targeting and Detection- Polymeric Nanoparticles for cancer treatment - mechanism of drug delivery to tumors -advantages and limitations - Multifunctional Agents - Cancer Imaging – Magnetic Resonance Imaging- Cancer Immunotherapy.

UNIT IV

NANOTECHNOLOGY IN COSMETICS

9
Polymers in cosmetics: Film Formers – Thickeners – Hair Colouring – Conditioning Polymers: conditioning, Cleansing – Silicons – Emulsions – Stimuli Responsive Polymeric Systems - Formulation of Nano Gels, Shampoos, Hair-conditioners -Micellar self-assembly Sun-screen dispersions for UV protection – Color cosmetics

UNIT V

NANOTOXICITY

9
NanoToxicology- introduction, dose relationship- Hazard Classification-Risk assessment and management - factors affecting nano toxicity- Dermal Effects of Nanomaterials, Pulmonary, Neuro and Cardiovascular effects of Nanoparticles - Gene–Cellular and molecular Interactions of Nanomaterials

TOTAL : 45 PERIODS

OUTCOMES: The students will be able to
• Comprehend the structural and functional principles of Pharmaceutical nanotechnology
• Recognize nanomaterials for analysis and sensing techniques
• Apprehend the biomedical applications of nanotechnology

TEXT BOOKS:
1. Springer Handbook of Nanotechnology- Ed. by B. Bhushan, Springer-Verlag 2004
2. Nanobiotechnology: Concepts, Applications and Perspectives,. CM.Niemeyer C A. Mirkin, (Eds) , Wiley, 2004
3. Nanotechnology: Health and Environmental Risks, Jo Anne Shatkin, Second Edition, CRC Press, 2013
4. Sarah E. Morgan, Kathleen O. Havelka, Robert Y. Lochhead “Cosmetic Nanotechnology: Polymers and Colloids in Cosmetics”, American Chemical Society, 2006.

REFERENCES:
1. Nanotechnology in Biology and Medicine: Methods, Devices and Applications, Tuan VoDinh, CRC Press, 2007
2. The Chemistry of Nanomaterials: Synthesis, Properties and Applications, C.N.R. Rao, A. Muller, A. K. Cheetham (Eds), Wiley-VCH Verlag 2004
3. Nanotechnology: Environmental Health and safety, Risks, Regulation and Management, Matthew Hull and Diana Bowman, Elsevier, 2010
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