PY8502 - PHARMACOLOGY AND CHEMOTHERAPY (Syllabus) 2017-regulation Anna University

PY8502 - PHARMACOLOGY AND CHEMOTHERAPY (Syllabus) 2017-regulation Anna University

PY8502

PHARMACOLOGY AND CHEMOTHERAPY

 LPTC

3003

OBJECTIVES:
• To provide the general pharmacological principles.
• To make understand the pharmacology of different types of drugs acting on various physiological systems.

UNIT I

GENERAL PHARMACOLOGY

12

Routes of administration, Pharmacokinetics, Pharmacodynamics, Factors modifying drug action, adverse drug reaction, drug interactions, Bioassay of drugs, drug discovery and development.

UNIT II

PERIPHERAL AND CENTRAL NERVOUS SYSTEM

12

Mechanism of action, Pharmacology of parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics, neuromuscular blocking agents, general anaesthetics, antipsychotics, antidepressants, antiepileptic, analgesics, antipyretic, anti-inflammatory (NSAIDS) and CNS stimulants.


UNIT III

CARDIOVASCULAR PHARMACOLOGY

12

Classification, Mechanism of action, Pharmacology of cardiac glycosides, antianginal, antihypertensive agents, vasodilators including calcium channel blockers, antiarrhythmic and anti- hyperlipidemic agents.

UNIT IV

GASTROINTESTINAL PHARMACOLOGY

10

Classification, Mechanism of action, Antacids, antiulcer drugs, laxatives, antidiarrhoeal, emetics, antiemetics, appetite stimulants and suppressants.

UNIT V

CHEMOTHERAPY AND ANTIMICROBIAL AGENTS

14

General principles of chemotherapy, sulphonamides, antibiotics – penicillins, cephalosporins, chloramphenicol, macrolides, fluoroquinolones. Chemotherapy of tuberculosis, leprosy, fungal, viral diseases, malignancy and immunosuppressive agents.

TOTAL : 60 PERIODS

OUTCOMES: The student will be able to
• Understand the various principles of general pharmacology.
• Understand the pharmacology of various categories of drugs acting on nervous, cardiovascular and gastrointestinal systems.
• Understand the principles of chemotherapy and pharmacology of antimicrobial agents.

TEXT BOOKS:
1. Tripathi, K.D., “Essentials of Medical Pharmacology”, 7th Edition, Jaypee Brothers Medical Publishers (P) Ltd, 2015.
2. Satoskar, R.S., Bhandarkar, S.D. and Rege, N., “Pharmacology and Pharmacotherapeutics”, 24th edition, Popular Prakashan (P) Ltd., 2015.
3. H. L. Sharma, K. K. Sharma, Principles of Pharmacology, Paras Medical Publishers, 3rd Edition, 2017.

REFERENCES:
1. Laurence L. Brunton, Bjorn C. Knollmann, RandaHilal-Dandan, " Goodman and Gilman S “The Pharmacological Basis of Therapeutics", 13thedition, McGraw-Hill Education / Medical, 2017.
2. Humphrey P. Rang,Maureen M .Dale ,James M .Ritter ,Rod J. Flower, Graeme Henderson, "Rang &Dale's Pharmacology", 8th edition, Churchill Livingstone, 2015.
3. Katzung, B.G., Trevor AJ. Basic and Clinical Pharmacology, McGraw-Hill Education, 13th Edition, 2015.

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