PY8601 - TECHNOLOGY OF SOLID DOSAGE FORMS (Syllabus) 2017-regulation Anna University

PY8601 - TECHNOLOGY OF SOLID DOSAGE FORMS (Syllabus) 2017-regulation Anna University

PY8601

TECHNOLOGY OF SOLID DOSAGE FORMS

 LPTC
4004

OBJECTIVE:
• To provide the concepts of various parameters involved in the formulation and development of various solid dosage forms.

UNIT I

POWDERS AND GRANULES

12
Advantages and disadvantages of powdered and granulated products, Mixing and dividing of powders, Problems in manufacturing powders, Effervescent granules, Reasons for granulation, Granulation mechanisms, Pharmaceutical granulation equipments.

UNIT II

TABLETS AND COATING

12
Types of tablets, Formulation, Manufacturing of tablets, Tableting problems, Evaluation of Tablets, Tablet coating,Film coating, Sugar Coating, Enteric coating, Evaluation of coated tablets, Applications, Large Scale Manufacture.


UNIT III

CAPSULES

12
Classification, Hard gelatin capsules, Composition and size, Materials and methods for production of hard gelatin capsule, Formulation and filling of capsules, Soft gelatin capsules, Rationale, Manufacturing and formulation of soft gelatin capsules,Evaluation of capsules.

UNIT IV

MICROENCAPSULATION

12
Types of microcapsules, Application of microencapsulation in pharmaceutical sciences, Microencapsulation by coacervation, Phase separation, Multi-orifice centrifugation, Spray congealing, Polymerization,Air suspension technique, Pan coating and other techniques,Evaluation of microcapsules.

UNIT V

ADVANCES IN TABLETING TECHNIQUES

12
Sustained release dosage forms,controlled release dosage forms-Compression coating – Inlay tablets, Layer tablets, Mouth dissolving tablet, Tablets in tablets.

TOTAL : 60 PERIODS

OUTCOMES: The student will be able to
• Comprehend the factors influencing the development of various solid dosage forms.
• Recognize the formulation concepts and evaluate different dosage forms to meet out the compendial requirements.
• Apprehend the advances in solid dosage forms

TEXT BOOKS:
1. Aulton, M.E., “Pharmaceutics – The Science of Dosage form Design”, 2nd Edition, ELBS Publications, 2002.
2. Indian Pharmacopoeia, Indian Pharmacopoeia commission, Ghaziabad, 2016
3. Cooper and Gunn's “Dispensing for Pharmaceutical Students”, Edited by S J Carter,CBS Publishers, New Delhi, 2008.

REFERENCES:
1. Liberman, H.A., Lachman, L. and Schwartz, J.B., “Pharmaceutical Dosage Form: Tablets”, 2nd Edition, Volume II, Mercel Dekker, 1999.
2. Gennaro, A.R., “Remington: The Science and Practice of Pharmacy”, Vol. I and II,21st Edition, Lippincott Williams and Willkins, 2005.
3. Banker, G.S. and Rhodes, C.T., “Modern Pharmaceutics”, 4th Edition, Informa Health Care, 2002.
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