FD3401 Syllabus - Biochemistry And Nutrition - 2021 Regulation Anna University
FD3401 Syllabus - Biochemistry And Nutrition - 2021 Regulation Anna University
FD3401 | BIOCHEMISTRY AND NUTRITION | LTPC |
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3003
COURSE OBJECTIVES:
The course aims to • Ensure students have a strong grounding in structures
and reactions of biomolecules.
• Introduce them to metabolic pathway of the major biomolecules.
• Enable the students to understand roles of each nutrients in growth and metabolism.
• Introduce them to metabolic pathway of the major biomolecules.
• Enable the students to understand roles of each nutrients in growth and metabolism.
UNIT I | INTRODUCTION TO BIOMOLECULES | 5 |
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Basic principles of organic chemistry, role of carbon, types of functional
groups, biomolecules, chemical nature of water, pH and biological buffers.
UNIT II | STRUCTURE AND PROPERTIES OF IMPORTANT BIOMOLECULES | 18 |
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Carbohydrates mutarotation, glycosidic bond, reactions of monosaccharides
and reducing sugars. Starch, glycogen, cellulose and chitin structures and
functions. Proteoglycans, glycosaminoglycans, hyaluronic acid, chondroitin
sulfate. Lipids Fatty acids, glycerol, triacylglycerol, phospholipids,
glycolipids, sphingolipids. Inherited metabolic disorders of
Lipid-metabolism-Tay-Saach’s disease, Niemann-Pick’s disease and Gaucher’s
disease. Cholesterol, steroids, Bile acids and salts, Gluco-and
Mineralocorticosteroids. Prostaglandins and their functions.Lipoproteins.
Cardiovascular disease and correlation with circulating lipid and
lipoprotein concentration Amino Acids, Peptides, and Proteins.
Classification based on side-chain properties. Structures, hierarchy of
organization primary, secondary, tertiary and quaternary structures,
glycoproteins, lipoproteins.Nucleic acids Purines, pyrimidines,
nucleosides, nucleotides, Chargaff’s Rules. Base pairing,A-T and G-C,
mRNA, rRNA and tRNA., Watson-Crick structure of DNA. reactions,
properties,Tm and hypochromicity, Measurement of DNA and RNA.
Nucleoprotein complexes.
UNIT III | AN OVERVIEW OF NUTRITION AND ENERGY BALANCE | 5 |
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Definition, six classes of nutrients, calculating energy values from food,
using the RDA, nutritional status, nutritional requirement, malnutrition,
nutritional assessment of individuals and populations, 66 dietary
recommendations, Balanced diet planning Diet planning principles, dietary
guidelines; Glycemic and Non-glycemic carbohydrates, health effects of
fiber and starch intake food groups, exchange lists, personal diet
analysis; Digestion, Absorption and Transport Anatomy and physiology of
the digestive tract, mechanical and chemical digestion, absorption of
nutrients. Energy balance; body weight and body composition; health
implications; obesity, BMR and BMI calculations.
UNIT IV | VITAMINS AND MINERALS | 4 |
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Water Soluble Vitamins B vitamins examined individually (Thiamine,
Riboflavin, Niacin, Pyridoxine, Biotin, folate B12, choline, pantothenic
acid, and carnitine) and in concert; B vitamin deficiencies, toxicities,
and food sources; vitamin C roles and recommended intake, deficiency,
toxicity and food sources. Fat Soluble Vitamins A, D, E, and K Function,
recommended intakes, toxicities, food sources of vitamin A, D, E, and K;
Water and Major Minerals Water balance and recommended intakes;
fluid/electrolyte balance, acid-base balance; function, recommended
intakes, and regulation of sodium, potassium, and calcium. Trace Minerals
Food sources, function, recommended intakes, toxicities, deficiencies and
transport of iron and zinc; importance of selenium, copper, fluoride, and
chromium.
UNIT V | INTERMEDIARY METABOLISM AND REGULATION | 13 |
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Enzymes, introduction to biocatalysts, metabolic pathways, primary and
secondary metabolites. Glycolysis, TCA cycle, gluconeogenesis, pentose
phosphate shunt, glyoxalate shunt, fatty acid synthesis and oxidation,
reactions of amino acids, deamination, transamination and decarboxylation,
urea cycle, Bioenergetics - High energy compounds, electronegative
potential of compounds, respiratory chain, ATP cycle, calculation of ATP
yieldduring oxidation of glucose and fatty acids.
TOTAL: 45 PERIODS
COURSE OUTCOMES:: Upon completion of the course, students will be able
to
At the end of the course the students would be able to CO 1 : Understand
the fundamentals of biomolecules, biochemical reactions in a living
organism. CO 2 : Understand the importance of nutrients in growth and
metabolism. CO 3 : Gain knowledge of importance of nutrients in
physiological function and biochemical pathways.
TEXT BOOKS:
1. Nelson, D.L. and M.M. Cox, “Lehninger’s Principles of Biochemistry”,
4th Edition, W.H. Freemen & Co., 2005. 2. Satyanarayana, U. and U.
Chakerapani, “Biochemistry” 3rd Rev. Edition, Books & Allied (P) Ltd.,
2006. 3. Rastogi, S.C. “Biochemistry” 2nd Edition, Tata McGraw-Hill, 2003.
4. Mann, Jim and Stewart Truswell “Essentials of Human Nutrition”. 3rd
Edition. Oxford University Press, 2007. 5. Gibney, Michael J., et al.,
“Introduction to Human Nutrition”. 2nd Edition. Blackwell,2009.
REFERENCES:
1. Berg, Jeremy M. et al. “Biochemsitry”, 6th Edition, W.H. Freeman & Co.,
2006. 2. Voet, D. and Voet, J.G., “Biochemistry”, 3rd Edition, John Wiley
& Sons Inc.,2004. 3. Gropper, Sareen S. and Jack L.Smith “Advanced
Nutrition and Human Metabolism”. 5th Edition. Wadsworth Publishing, 2008.
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