OBT353 Syllabus - Basics Of Biomolecules - 2021 Regulation - Open Elective | Anna University

OBT353 Syllabus - Basics Of Biomolecules - 2021 Regulation - Open Elective | Anna University

OBT353	BASICS OF BIOMOLECULES	L T P C

3003

OBJECTIVES:

• The objective is to offer basic concepts of biochemistry to students with diverse background in life sciences including but not limited to the structure and function of various biomolecules and their metabolism.

UNIT I	CARBOHYDRATES	9

Introduction to carbohydrate, classification, properties of monosaccharide, structural aspects of monosaccharides. Introduction to disaccharide (lactose, maltose, sucrose) and polysaccharide (Heparin, starch, and glycogen) biological function of carbohydrate.

UNIT II	LIPID AND FATTY ACIDS	9

Introduction to lipid, occurrence, properties, classification of lipid. Importance of phospholipids, sphingolipid and glycerolipid. Biological function of lipid. Fatty acid, Introduction, Nomenclature and classification of fatty acid Essential and non essential fatty acids.

UNIT III	AMINO ACIDS AND PROTEIN.	9

Introduction to amino acid, structure, classification of protein based on polarity. Introduction to protein, classification of protein based on solubility, shape, composition and Function. Peptide bond– Structure of peptide bond. Denauration – renaturation of protein, properties of protein. Introduction to lipoprotein, glycoprotein and nucleoprotein.Biological function of protein.

UNIT IV	NUCLEIC ACIDS	9

Introduction to nucleic acid, Difference between nucleotide and nucleoside, composition of DNA & amp; RNA Structure of Nitrogen bases in DNA and RNA along with the nomenclature· DNA double helix (Watson and crick) model, types of DNA, RNA.

UNIT V	VITAMINS AND HORMONES	9

Different types of vitamins, their diverse biochemical functions and deficiency related diseases. Overview of hormones. Hormone mediated signaling. Mechanism of action of steroid hormones, epinephrine, glucagons and insulin.Role of vitamins and hormones in metabolism; Hormonal disorders; Therapeutic uses ofvitamins and hormones.

TOTAL: 45 PERIODS

OUTCOMES:

• Students will learn about various kinds of biomolecules and their physiological role.
• Students will gain knowledge about various metabolic disorders and will help them to know the importance of various biomolecules in terms of disease correlation.

TEXT BOOKS:

1. Lehninger Principles of Biochemistry 6th Edition by David L. Nelson, Michael M. Cox W.H.Freeman and Company 2017
2. Satyanarayana, U. and U. Chakerapani, “Biochemistry” 3rd Rev. Edition, Books & Allied (P) Ltd., 2006. 3. Rastogi, S.C. “Biochemistry” 2nd Edition, Tata McGraw-Hill, 2003.
4. Conn, E.E., etal., “Outlines of Biochemistry” 5th Edition, John Wiley & Sons, 1987.
5. Outlines of Biochemistry, 5th Edition: By E E Conn, P K Stumpf, G Bruening and R Y Doi.pp 693. John Wiley and Sons, New York. 1987.

REFERENCES:

1. Berg, Jeremy M. et al. “Biochemsitry”, 6th Edition, W.H. Freeman & Co., 2006.
2. Murray, R.K., etal “Harper’s Illustrated Biochemistry”, 31st Edition, McGraw-Hill, 2018.
3. Voet, D. and Voet, J.G., “Biochemistry”, 4th Edition, John Wiley & Sons Inc., 2010.