OPY351 Syllabus - Pharmaceutical Nanotechnology - 2021 Regulation - Open Elective | Anna University

OPY351 Syllabus - Pharmaceutical Nanotechnology - 2021 Regulation - Open Elective | Anna University

OPY351	PHARMACEUTICAL NANOTECHNOLOGY	L T P C

3003

COURSE OBJECTIVES:

• The goal of this course is to provide an insight into the fundamentals of nanotechnology in biomedical and Pharmaceutical research. It will also guide the students to understand how nanomaterials can be used for a diversity of analytical and medicinal rationales.

UNIT I	NANOSTRUCTURES	9

Preparation, properties and characterization - Self-assembling nanostructure - vesicular and micellar polymerization-nanofilms - Metal Nanoparticles- lipid nanoparticles- nanoemulsion - Molecular nanomaterials: dendrimers, etc.,

UNIT II	NANOTECHNOLOGY IN BIOMEDICAL INDUSTRY	9

Reconstructive Intervention and Surgery- Nanomaterials in bone substitutes and dentistry – Implants and Prosthesis -in vivo imaging- genetic defects and other disease states –– Nanorobotics in Surgery –Nanocarriers: sustained, controlled, targeted drug delivery systems.

UNIT III	NANOTECHNOLOGY IN CANCER THERAPY	9

Cancer Cell Targeting and Detection- Polymeric Nanoparticles for cancer treatment – mechanism of drug delivery to tumors -advantages and limitations - Multifunctional Agents - Cancer Imaging – Magnetic Resonance Imaging- Cancer Immunotherapy.

UNIT IV	NANOTECHNOLOGY IN COSMETICS	9

Polymers in cosmetics: Film Formers – Thickeners – Hair Colouring – Conditioning Polymers: conditioning, Cleansing – Silicons – Emulsions – Stimuli Responsive Polymeric Systems - Formulation of Nano Gels, Shampoos, Hair-conditioners -Micellar self-assembly Sun-screen dispersions for UV protection – Color cosmetics.

UNIT V	NANOTOXICITY	9

NanoToxicology- introduction, dose relationship- Hazard Classification-Risk assessment and management - factors affecting nano toxicity- Dermal Effects of Nanomaterials, Pulmonary, Neuro and Cardiovascular effects of Nanoparticles - Gene–Cellular and molecular Interactions of Nanomaterials.

TOTAL: 45 PERIODS

COURSE OUTCOMES: The student will be able to

CO1 : Identify the process for the preparation and characterization of the different nanostructured materials.
CO2 : Apply the nanotechnology in biomedical discipline with related to drug delivery and disease diagnosis.
CO3 : Develop the process, experiments and apply in identifying in a societal and global context. CO4:Design and develop the process with suitable equipment for the preparation of nanomaterials in developing cosmetic products.
CO5 : Understand the ethical principles to confirm the safety of the nano products with respect to risk assessment and its management.
CO6 : Have the knowledge about nanotechnology products and its different applications in a societal and global context.

TEXT BOOKS:

1. Springer Handbook of Nanotechnology- Ed. by B. Bhushan, Springer-Verlag 2004.
2. Nanobiotechnology: Concepts, Applications and Perspectives,. CM.Niemeyer C A. Mirkin, (Eds) , Wiley, 2004.
3. Nanotechnology: Health and Environmental Risks, Jo Anne Shatkin, Second Edition, CRC Press, 2013.
4. Sarah E. Morgan, Kathleen O. Havelka, Robert Y. Lochhead “Cosmetic Nanotechnology: Polymers and Colloids in Cosmetics”, American Chemical Society, 2006.

REFERENCES:

1. Nanotechnology in Biology and Medicine: Methods, Devices and Applications, Tuan VoDinh, CRC Press, 2007.
2. The Chemistry of Nanomaterials: Synthesis, Properties and Applications, C.N.R. Rao, A. Muller, A. K. Cheetham (Eds), Wiley-VCH Verlag 2004.
3. Nanotechnology: Environmental Health and safety, Risks, Regulation and Management, Matthew Hull and Diana Bowman, Elsevier, 2010.